The Waskaganish biodiversity reserve is located in the Nord-du-Québec administrative region, between 51°21’ and 51°38’ north latitude and 77°18’ and 78°52’ west longitude. It is situated some 40 km east of the Cree village of Waskaganish, within Baie-James Municipality. The protected area covers an area of 1,062.7 km2. Its’ eastern portion is accessible by Route 109, which runs through it over short distances.